[duke]

making cannabis oil for medicine
hi all well this is how i make our"superoil" is made,strains used were
1.whitewidowxbigbud
2.afghanxkush
3.chiesel trim and popcorn
4.automazar
5.blue rhino trim and popcorn
in total 16oz was used to produce aprox 20ml of "superoil" i tried the tiniest blob in the glass pipe and it is absolutely lethal,i dont think i will be doing much else today!
i have done photos dont no how well or not they came out but this is how i make iso oil intended for medical use as opposed to purely recreational,i believe the main thing is that for medical use that you use suitable solvent either isopropyl alcohol 99.9%,or acetone,or petroleum ether if you can source it.
this extraction is using isopropyl from ebay cost £20 delivered,
1.sort and oven dry at 100deg c for 2-3 hours until completely dry,this also decarboxylates or activates the cannabinoids we are after for medicine i will explain the need for this a bit later, now we bag and freeze all trim or bud overnight also the isopropyl,this lessens the amount of green material extracted.
2.prepare the following,1 rice cooker,2 funnels,coffee filter,wooden spoon or stick,plastic bucket,gloves if needed,2 jugs pref glass,disposable syringes,
once you have got your bits together you dont want to hang about,the longer the iso is in the trim bud the more green matter is extracted,so take your plastic bucket,empty in your frozen bud/trim add iso to cover contents using your wooden spoon move the contents about for 30 seconds,leave 1min,stir again,now take your coffee filter and funnel and filter the iso through if as i do you use 2 jugs and filters its slightly quicker,this is the tedious bit!
3.once all the iso has been filtered its time to switch on your rice cooker,first you need it near the window or door,you must have a fan blowing outdoors and no naked flames,or spliffs!if your in a kitchen with gas boiler make sure to turn it of as the fumes from iso will explode!now fill the rice cooker with the iso about 2-3rds full,start on high setting at no time ever leave it unattended,if you do and it boils dry it will destroy your oil!during this time the level in the cooker can drop very quickly.once you have evaporated the majority of the solvent and the level has dropped significantly turn the cooker to low setting,take 2-3 drops of water and drop them in the pot,this helps to evap of the last bit of solvent,without burning the precious oils.leave on low setting watching till it no longer has bubbles,depending on the type of strains and wether bud or trim was used seems to make difference in how long it takes,but ime not longer than2 hours.
4.take syringe pull out the plunger and pour the still warm oil in the syringe,first time i spent ages trying to suck it into syringe,but in the end decided it easier to remove the plunger and fill it that way,anyway you do it its messy,sticks to everything and ends up gluing your mitts!pics will be added to this just for clarification,i hope this proves of use to someone,peace all.
 [/HR]

[duke]

Decarboxylation of cannabis The following information about decarboxylation was not written by Cannabis Chris, but was pulled from another site during part of my research for “Marijuana Decarboxylation: how to decarboxylate medical marijuana” and “What is Decarboxylation?“, as well as a future article with another method. This snippet about decarboxylation had too much good information for me to leave out. After reading this information, along with a graph that shows decarboxylation temperatures, I will be doing some experimenting with a few more methods of decarboxylating marijuana and I will post the results here. Anyway, here is some great information from one of the big pharma companies, about the decarboxylation process, some of the info is pretty boring, but please read it all. That way you will have the best understanding of the decarboxylation method you choose to go with… … “The decarboxylation step may be carried out prior to or after extraction with liquid CO2. In a preferred embodiment the decarboxylation step … is conducted by heating the plant material to temperatures and for times which ensure at least 95% conversion of the acid cannabinoids from the acid form to their neutral form whilst ensuring thermal degradation of THC to CBN is less than 10%. Decarboxylation of cannabinoid acids is a function of time and temperature, thus at higher temperatures a shorter period of time will be taken for complete decarboxylation of a given amount of cannabinoid acid. In selecting appropriate conditions for decarboxylation consideration must, however, be given to minimising thermal degradation of the desirable, pharmacological cannabinoids into undesirable degradation products, particularly thermal degradation of THC to cannabinol (CBN). Preferably, decarboxylation is carried out in a multi-step heating process in which the plant material is: i) heated to a first temperature for a first (relatively short) time period to evaporate off retained water and allow for uniform heating of the plant material; and ii) the temperature is increased to a second temperature for a second time period (typically longer than the first time period) until at least 95% conversion of the acid cannabinoids to their neutral form has occurred. Preferably the first step is conducted at a temperature in the range of 100° C. to 110° C. for 10–20 minutes. More preferably the first temperature is about 105° C. and the first time period is about 15 minutes. If the plant material is derived from cannabis plants having a high CBD content (defined as >90% CBD as a percentage of total cannabinoid content), the second temperature is preferably in the range from 115° C. to 125° C., preferably about 120° C. and the second time period is in the range from 45 to 75 minutes, preferably about 60 minutes. More preferably the second temperature is in the range from 135° C. to 145° C., preferably 140° C. and the second time period is in the range from 15 to 45 minutes, preferably about 30 minutes. In another embodiment, most preferred for a mass of plant material greater than 4 kg, the second temperature is in the range from 140° C. to 150° C., preferably 145° C. and the second time period is in the range from 55–90 minutes. The latter conditions are preferred for processing amounts of, for example, 4–6 kg of starting plant material and the exact figures, particularly time, may vary slightly with increased mass. If the plant material is derived from cannabis plants having a high THC content (defined as >90% THC as a percentage of total cannabinoid content), the second temperature is preferably in the range of 115° C. to 125° C., typically 120° C., and the second time period is preferably in the range of 45 minutes to 75 minutes, typically about 60 minutes. More preferably the second temperature is in the range of 100° C. to 110° C., typically 105° C., and the second time period is in the range of 60 to 120 minutes. In another embodiment, most preferred for a mass of plant material greater than 4 kg, the second temperature is in the range of 140° C. to 150° C., preferably 145° C., and the second time period is in the range of 45 to 55 minutes. Most preferably the decarboxylation step is conducted at temperatures and for times which ensure at least 97% conversion of the acid cannabinoids to their neutral form, whilst ensuring thermal degradation of THC to CBN is less than 5%. … The plant material used as the starting material for the extraction process is preferably ground, milled or otherwise processed to give a particle size of less than 2 mm, but preferably greater than 1 mm. Such treatment generally results in improved extraction of cannabinoids from the plant material, as packaging density is improved.” via Extraction of pharmaceutically active components from plant materials – GW Pharma Limited. … I really like the detailed information on the decarboxylation process here. The 2-stage temperature method seems to be worth looking into. If this information sparks any new methods of decarboxylation for you, then please comment with your method and results. [...] In order to give you the desired effect (psychoactive ability) , the cannabinoids in the marijuana material need to be activated. When THC is in it’s natural plant form, it is actually called THC-A, and does not get us high or medicated until it is heated past a certain temperature for a determined length of time. During the heating process, a reaction called decarboxylation takes place and removes the -A(carboxylic acid) part of the THC chain. Once the carboxylic acid is removed, the THC is psychoactive and is available for human uptake. Read more about the decarboxylation The Lesser Known Cannabinoid We all know that marijuana contains the cannabinoid THC or delta 9- tetrahydro cannabinol, having been told that is what gets you high and experiencing its wondrous effects. We as growers cultivate cannabis for the purpose of getting the high it creates when consumed and usually have the desire to obtain strains with the highest THC content possible. With all of the knowledge people are gaining from testing the marijuana plant we now know that cannabis has around 85 cannabinoids, so the general public only being familiar with one of them seems crazy. Royal Queen Seeds is an European company that sells CBD oil for medicinal purposes. The THC content in this olive oil based product is < 0.2% so users don’t get high at all. In today’s world with the cannabis culture growing rapidly, ground breaking scientific tests are beginning to be done all over the world and we are learning that there is much more to be discovered within the contents of this magical plant. One of the biggest discoveries found with modern research was with the second most concentrated cannabinoid - Cannabidiol, abbreviated CBD. THC and CBD are the two most abundant naturally occurring cannabinoids with THC accounting for 12-25% and CBD for >1-4% on average. If only a quarter of what researchers are saying about CBD is true then this medical breakthrough can have as large an impact on modern natural medicine as the discovery of antibiotics. CBD is like a brother or sister to THC, because like all siblings sometimes you work symbiotically together and sometimes you’re combating or off setting one another. Unlike Cannabidiol, THC is a psychoactive compound (meaning it affects brain function by acting on the central nervous system, which can result in altering your mood, behavior, perception and cognition) and its effects are what users of cannabis feel the most when smoked. The high is responsible for the feeling of relaxation, the heightening of your senses and of course the inevitable snacking you shall do when it gives you a craving for the munchies. It also has medicinal uses for a multitude of symptoms including; mild to moderate pain, insomnia, depression, nausea and appetite loss, just to name a few. For some people though THC may cause anxiety or paranoia, often related to the feeling of time slowing down, which it of course is not. The CBD is considered a non-psychoactive cannabinoid, although it may seem to have some psychoactive effects, it emits a high that is sedative and responsible for the relief most people look for medicinally. Its medicinal uses surpass those of any other cannabinoid we know of, including; reducing or preventing inflammation and nausea, diabetes, alcoholism, PTSD, schizophrenia, rheumatoid arthritis, epilepsy, cardiovascular disease, anti-psychotic, anti-anxiety and even as a pain killer against muscle spasms or neuropathic pain, which are traditionally harder to treat with any medicine, even pharmaceutically. While both the THC and CBD cannabinoids individually have many beneficial properties when they are used together, as they come from the marijuana plant, their effects are far more impressive. When working alongside of the THC molecules CBD can negate some of the anxiety that THC causes as well as give relief for different types of pain than THC can. This makes nature the best doctor by combining them into a single plant because they are way more effective when administered together, especially for people with multiple symptoms. CBD appears to also antagonize the excitatory effects of THC by delaying the onset of the high, while also making it last as much as twice as long. Some of us refer to that as ‘creeper’ bud when the effect doesn’t seem to be there after consumption, but then all of a sudden…BOOM…it comes out of nowhere slamming you like a ton of bricks. Although marijuana does affects some people different than others, it likely you have experienced these antagonized effects. Mammals, birds, reptiles and fish all have endocannabinoid compounds made by their bodies which are basically a “natural” produced THC called anandamide. Technically, anandamide (Ananda = bliss in Sanskrit + amide = chemical type) is a naturally occurring neurotransmitting compound that our bodies have circulating within them. Both THC and anandamide act thru cannabinoid receptors located on cells throughout our bodies and have similar effects on things such as; pain, appetite and memory. Receptors are merely gate keeper proteins embedded in cells that direct chemical signals from outside molecules into the cell, telling them to do something, kind of like an air traffic controller for our cells, but this communication only happens after a molecule or compound binds to them. A molecule that binds to a receptor is called a ligand and the receptors are very specific when it comes to what can bind to it and only certain compounds will bind to each type of receptor. It’s like a lock and key, only certain keys open specific doors and when the door is open you have a gateway, and in the case of receptors it’s a gateway for a directional signal. One single cell can have many different types of receptors attached to it that are made to communicate with different compounds. Cannabinoids only affect us because our bodies contain these receptors that are made to bind to specific cannabinoid molecules. Human brains actually contain more cannabinoid receptors than any other G-protein coupled receptor! Our cells containing so many of these that bind specifically with the THC on top of the fact that our bodies produce their own form of “natural THC” (anandamide) however tiny the concentration, makes a lot of sense out of the fact that humans are so drawn to this plant. There is nothing unnatural about the utilization process our bodies go through with cannabinoids and marijuana is proving itself to be a very effective natural medicine and it should be available for use to patients who need it. So far there are only two known cannabinoid receptors in our body that bind with THC; the CB1 receptors which are found in the brain and central nervous system, and the CB2 receptors that are distributed throughout the body, but mostly in the immune system. Other than the cannabinoids found in cannabis (which are of course the most powerful) and the ones our body naturally produces there are many other substances that minutely affect our internal endocannabinoid system, such as; Echinacea, turmeric, black pepper, cacao etc. These and few other consumables have also been found to bind with these same cannabinoid receptors. Cannabidiol or CBD however, does not have much binding affinity to either of the two known cannabinoid receptors. It instead has a suppressive effect on the enzyme FAAH (or ‘fatty acid amide hydroxylase’) which is the enzyme responsible for breaking down and destroying anandamide. This suppressive reaction with CBD means that more anandamide will stay in your system and for longer periods of time. Anandamide favors the CB1 receptor, as does THC, therefore leaving fewer openings for the action of the THC binding to those receptors and in turn less of an effect. While CBD doesn’t care to bind with CB1 or CB2 it has been shown to interact with other receptors to enable its medicinal effects. There are a couple G-protein receptors located in the central and peripheral nervous systems that interact with CBD. Then there is the TRPV-1(technical abbreviation for ‘transient receptor potential cation channel subfamily V’) that reacts to it. The TRPV-1 receptor which also is activated by capsaicin, the ‘hot’ compound found in chili peppers, is known to mediate pain perception, inflammation and body temperature, as you have probably felt some of these effects from eating a very hot pepper. A big roll is played in anxiety within our bodies by the family of 5-HT receptors, which are activated by the neurotransmitter serotonin. These receptors trigger responses via chemical messages that are either excitatory or inhibitory depending on the chemical context of the bind. The 5-HT1A serotonin receptor is member of that receptor family that binds to CBD and when activated by it exerts the cannabinoids heavy anti-depressant effects, which then trickles down into some of the other medicinal functions CBD gives because this receptor also works in a wide array of processes including anxiety, addiction, appetite, sleep, pain perception, nausea, vomiting etc. It does this by activating an inhibitory response, slowing down its signaling, compared to other drugs like LSD, mushrooms and hallucinogens alike that activate a different 5-HT receptor producing an excitatory response. CBD emits some of its anti-anxiety effects by activating receptors called adenosine receptors. These regulate cardiovascular functions, myocardial oxygen consumption and coronary blood flow, opening up many of the symptoms of anxiety; tenseness, tightness in the chest, shortness of breath etc. These receptors are significant regulators in the brain for other neurotransmitters like dopamine and glutamate. Dopamine is not only responsible for inducing pleasurable feelings but can affect sleep, mood, memory, attention and voluntary movement. Other drugs such as cocaine and methamphetamine act by amplifying the effects of dopamine receptors as well but on a way larger scale. While THC temporarily enhances dopamine levels CBD does not, it has only been found to be sporadic in research done on mice and rats mostly working as an inhibitor. More research is needed into why this is and how it only happens randomly. Maybe it’s related to one of the other 83 cannabinoids we know so little about. Both CBD and THC individually have been proven to work against cancer, but they have synergy when combined. We are in need of enhanced clinical trials to pinpoint exactly what functions they have when they are working together in the form of cannabis. Due to the unfortunate fact that cannabis cultivation and use is still restricted or forbidden in most parts of the world today, leads to the lack of funding and resources needed from governments and agencies to do such research. While there have been some university and collegiate studies done across the globe that compile enough compelling evidence pointing to a possible lead on the cannabis/cancer relationship, it is not definitive as of yet. This possible lead involves another G-protein coupled receptor called the GPR55, sometimes referred to as the orphan receptor because it hasn’t been scientifically placed into a family of receptors although many researchers believe it to be a third cannabinoid receptor. The GPR55’s are mainly found throughout the brain, with a concentration in and around the cerebellum and it is utilized regulating bone density and blood pressure. One example is when you have an overactive GPR55 receptor its signaling is increased and can be linked to osteoporosis. The receptor promotes osteoclast cell behavior, and osteoclast is responsible for bone reabsorption, a process in which bone calcium is broken down and transferred from the bone to the blood, rendering it weaker. This receptor when activated also aids in the rapid growth (proliferation) of cancer cells and has been linked to many different types of cancer. CBD has been shown in some studies to block GPR55 signaling, thereby decreasing both cancer cell proliferation as well as bone reabsorption and exerting its anti-cancer effects. Most tests for illegal cannabis are tests for THC and in most countries CBD by itself is completely LEGAL and you can purchase it in many forms by itself. Unfortunately it will not have all of the same effects it would if it was in the combinations found in cannabis but it can work medicinal wonders even on its own. University studies have proved that it has tremendous effects on mice reducing rheumatoid arthritis inflammation by 50% and even reducing the infarct (necrosis) size by 65% when taken immediately after a heart attack.

[duke]

The high felt from CBD rich plants (or edibles) is generally felt more in the body, whereas THC high effects are felt more so in the head but these can vary depending on the CBD:THC ratios. The differences can be somewhat easily distinguished when comparing the feeling of smoking cannabis to eating an edible cannabis treat. This is because of several reasons; one being that there is more CBD found in the leaves of the plant than in the buds and most of us save the buds to smoke and use the leaf trim to bake with, two because when heated THC begins to burn off at 150-157 degrees Celsius while its counterpart cannabinoid CBD holds a threshold of 160-180 degrees required to begin to burn off. I don’t know about you but I don’t know of many brownie recipes that bake at less than 150 degrees and unless you are privy to the knowledge of adjusting the baking times and temps you are most likely eating treats filled with CBD. The stems also contain more CBD than the buds do making it worthwhile to utilize the whole plant. Contrary to what some people believe a plant cannot be made into a CBD rich plant if it lacks the genetic make up to do so. The ratios of THC, CBD and all other cannabinoids are genetically pre-determined. The fact that there are very few high CBD producing plants is a bummer (a high percentage means anything over just 4%) this is a direct result of years of cross breeding plants for a high THC content. There are only 25-30% of the seed stock available today that have the potential to be CBD rich strains (i.e. >4%). When those potential strains create batch of seeds, that batch will then produce several different phenotypes of seedlings, creating both CBD rich and THC rich plants in each generation. On average one out of every four seeds derived from a CBD rich cannabis plant will create a CBD rich phenotype seedling. Even on the rarest of occasions you may get a two out of every four scenario, leaving you with a 25-50% CBD dominate seedlings possibility. The only easy way to proliferate a CBD rich strain is to find one of those dominant phenotypes and grow it into a mother plant to cut clones from, all of the clones will contain the exact CBD:THC ratio as the mother or donor plant. . How do you even know if you have a CBD rich strain? There are chemical compound tests that can be done on vegetative plants to identify seedlings that have CBD rich characteristics. These tests allow breeders insight into the CBD:THC ratios without having to wait until harvest time to test the flowers/buds. When you have harvested bud sample you want to test for cannabinoid percentage there are basically two testing methods to employ; quantitative or qualitative. The difference between these two testing methods can be familiarized by comparing the two to quality vs. quantity. you can even get at home test kits now. The methods growers have used in the past trying to achieve their plants top CBD potential are not proven to work and can tend to have a teeter totter effect decreasing the amount of THC in your plants as it transforms into another type of tetrahydrocannabinol called CBN. The one method I’ve found a lot of growers talking about is to let your plants over-flower, by this I mean let them go past their normal harvesting time, letting the trichromes become fully amber everywhere you can see with a microscope. While letting your plants go into extended flowering times is thought to increase CBD production there is no research to back up this claim and each day you go past the milky trichrome stage you are also losing THC as it degrades or oxidizes into CBN. The probable answer looms that it could just be the ageing or change of THC into CBN that may leave you feeling more of the CBD effects without actually increasing anything. Or that CBN will leave you feeling more groggy and sleepy than THC does. The THC to CBN transformation also happens during the drying process to some extent, decreasing the amount of THC as the buds age. My research has only revealed a few well known CBD rich strains, they are rare and said to have >4-15% Cannabidiol; charlotte’s web, harlequin, sour tsunami & cannatonic. But as the knowledge about what Cannabidiol does spreads, the need and want for cannabis as a medicine will grow immensely and that’s when breeders will really jump on making more. But if you’re the grower to take what we have learned and select the right parent strains, cross breed those for phenotype selection and get a mother plant to support a brand new strain with the highest CBD content ever, you may even become the literal Doctor Green thumb to our growing culture.

[Lousizzle]

fuck im high as shit it looks liek the matrix ....

[WanderinBloke]

Hi Duke

Is fresh frozen buds good for this. What I mean by fresh frozen. Cut from the plant and bagged and frozen. Is this suitable to make oil with.

Would I thaw this out before putting in the oven to decarb, or can this go straight in the oven?
Can I use a pan that is sat on a induction cooker to heat off the solvent rather than a rice cooker?
Do you use non bleached filters or do you not go to that extent?
I have a durable 90 micron Purify Filter bag, could I use this instead?

Thanks @duke

 

Hey bud. While duke's not here I'll jump in.

 

I've always used dry weed, very dry. Not seen anyone use wet/frozen weed so couldnt comment on the effectiveness, but if everyone is using dry that's the route I'd go.

 

Thaw, dry, then decarb the weed. Alternatively: thaw, dry, make oil, decarb oil.

 

You can use any heat source you like as long as you can be safe. No fumes should come into contact with your heat source, those fumes are VERY flammable; can't emphasize that enough. Extraction and clear airflow is paramount. Ideally you do this outside, but sometimes that's just not an option. I cook mine off in a rice cooker on a window sill with a big desk fan pointing at the cooker and blowing the fumes out the window. I also open other doors and windows for a good airflow backing up what the fan is doing. Consequently I can only cook when the wind is right

 

I use unbleached filters and they do the job just fine. Never used any others.

 

Apparently paper coffee filters are ~10-20 microns so your bag will let through too much crap.

 

Hope that helps, fella. Good luck and be safe!

Edited by WanderinBloke, 25 May 2015 - 10:08 PM.

[duke]

Hi Duke

Is fresh frozen buds good for this. What I mean by fresh frozen. Cut from the plant and bagged and frozen. Is this suitable to make oil with.

Would I thaw this out before putting in the oven to decarb, or can this go straight in the oven?
Can I use a pan that is sat on a induction cooker to heat off the solvent rather than a rice cooker?
Do you use non bleached filters or do you not go to that extent?
I have a durable 90 micron Purify Filter bag, could I use this instead?

Thanks @duke

see below!

 

Hey bud. While duke's not here I'll jump in.

 

I've always used dry weed, very dry. Not seen anyone use wet/frozen weed so couldnt comment on the effectiveness, but if everyone is using dry that's the route I'd go.

 

Thaw, dry, then decarb the weed. Alternatively: thaw, dry, make oil, decarb oil.

 

You can use any heat source you like as long as you can be safe. No fumes should come into contact with your heat source, those fumes are VERY flammable; can't emphasize that enough. Extraction and clear airflow is paramount. Ideally you do this outside, but sometimes that's just not an option. I cook mine off in a rice cooker on a window sill with a big desk fan pointing at the cooker and blowing the fumes out the window. I also open other doors and windows for a good airflow backing up what the fan is doing. Consequently I can only cook when the wind is right

 

I use unbleached filters and they do the job just fine. Never used any others.

 

Apparently paper coffee filters are ~10-20 microns so your bag will let through too much crap.

 

Hope that helps, fella. Good luck and be safe!

hi as wb says i wouldnt use fresh frozen as there is far to much moisture and also your oil will be pea green and dyes skin if used as ointment,i have been trying a new iso extraction method which uses much longer soak/wash times in a frozen extraction which makes very good medical oil and will do a thread on it shortly,peace

[WanderinBloke]

see below!

 

hi as wb says i wouldnt use fresh frozen as there is far to much moisture and also your oil will be pea green and dyes skin if used as ointment,i have been trying a new iso extraction method which uses much longer soak/wash times in a frozen extraction which makes very good medical oil and will do a thread on it shortly,peace

 

As duke says, freezing your ingredients (both ISO and weed) is the way forward. You get a much cleaner oil. Normally, when Ive not frozen ingredients the iso solution is green. Here's a batch a I made a few days ago with frozen bits:

 

 

No hint of green

[2scoops]

Is their any reason why you`ve not evaporated it yet if it was done a few days back @WanderinBloke  ?

[WanderinBloke]

Is their any reason why you`ve not evaporated it yet if it was done a few days back @WanderinBloke  ?

 

Am a lazy bastard

[2scoops]

Am a lazy bastard

 

I nearly added "or is it cus you just lazy and no particular reason" on the end, cheers anhyhow nice one. But u just thought it maybe another new fandango type trick for getting best of your mux/oil or whatever else.